casean protein isolate or concentrate? [Archive]

Kino

September 23rd, 2004, 02:03 PM

This is more than you asked for but...I learned alot a while ago from this one article. Somebody may not be happy with my posting this due to the products named, but I'm only doing so in the spirit of sharing information. Also, please try to keep in mind, that many of the powders named will carry a premium price tag.

5 STAR PROTEINS
These Are The Strongest Proteins In The World!
by Terry Giles, Eric Serrano, M.D., Phil Connolly and Jeff Everson

With exercise, some scientists have demonstrated that individuals working with weights, using high protein, actually increase their protein synthesis rate by over 35% and conversely, those eating low protein nutrition have only about a 10% increase in protein use rate. In terms of anti-catabolic action, scientists have shown that protein degradation or breakdown is reduced by over 60% with high protein nutrition as compared to low protein nutrition groups.

Back about 1998, researchers at Kent State University stated that the roles of any additional required dietary proteins are likely to be quite different for those in endurance exercise versus muscle building. Endurance work dictates that protein is required as an auxiliary fuel source, so that internal structural sources such as hemoglobin and the gut themselves are not catabolized for protein.

Strength exercise requires higher amounts of protein, absolutely, to augment additional muscle development and myofiber tissue repair. In essence, all athletes who work out benefit from higher protein content. Proteins, of course, are used for everything, for structure, in enzymatic reactions, for neuro-transmissions, immune system support, for transporting oxygen and for all intra-cell and extra-cell reactions necessary for life, and to build muscle.

SUPPLEMENTAL PROTEINS THAT BUILD MUSCLE BEST!

A wide array of non-biased experts have reached agreement-consensus, on the better commercial proteins. Those who have provided us with proven lab tests and that we can consider top-end include:

Anabolic category - whey isolates:

• Bioplex

• Vpx Zero Carb Whey

• Optimum's 100% Instantized Whey

Anabolic category - whey isolates, hydolysates and concentrates with additional proteins:

• Optimum Pro Complex

• Beverly Muscle Provider

Anticatabolic category - mixed blend with whey, egg and caseinates/other:

• Beverly Ultra Size

• CA Labs Pure Gro

• Priced Right Proteus 8

• Labrada Lean Body

• MET-Rx

• HDT Pro-Blend

• Prolab Lean Mass Matrix

• Beverly 100% Egg

• Prolab Lean Matrix

Anticatabolic category - mixed blend as above with low temperature micellar casein/extras:

• Dorian Yates Approved ProPeptide

• VPX Micellean Bioactive Food

Our industry’s commercial proteins exist as varying forms of milk isolates, caseinates, micellar casein, meat and fish, whole egg, egg albumin, (whites) whey concentrate, isolate or hydrolysate, soy isolates and other vegetable proteins, even collagen proteins. Various rating indices include PER (protein efficiency ratio), NR (nitrogen retention), BV (biological value), NPU (net protein utilization) and PDCAAs (predicted total amino acid score).

PER measures weight gain per weight of protein eaten. BV relates to the proportion of absorbed nitrogen that is retained for maintenance or growth. Internal body nitrogen dynamics are more complex than just measuring BV or PER.

Far more important is the NPU, the rate and the amount of nitrogen that actually gets to your muscle cells. The amount and the rate at which amino acids are absorbed through the gut and lower intestine, as well as the diet, exercise, local metabolic environment of the myofiber, may better determine the end synthesis of muscle.

A: Tops in whey category based on purity, quality, lab tests, etc:

• OPTIMUM Augmented Protein System (Pro Complex) mixed whey, egg albumin, glutamine peptides).

• BEVERLY MUSCLE PROVIDER: mixed whey, high in hydrolysates, glutamine, egg albumin.

• BIOPLEX: 90 plus percent pure filtered whey isolates).

Whey proteins, concentrates, filtered isolates and hydolysate or peptide forms of whey, are digested and absorbed at a fairly rapid rate. Well-manufactured, quality whey provides amino acids into the bloodstream rapidly and to best utilize whey, you really should take whey powders every 2-4 hours and never on an empty stomach.

According to the landmark study, Slow and Fast Dietary Proteins Differently Modulate Postprandial Accretion by Boirie, whey protein is burned (oxidized) almost as much as it is used for protein synthesis. This especially occurs on an empty stomach.

Many athletes are brainwashed that the only important meal is post training. In reality, as Jeff Everson wrote, as far back as 1985, the meal eaten before training is as important, as food at the mouth doesn’t mean muscle cell absorption. That complete process on an average, mouth to inside the muscle cell at the sites of the ribosomes and mitochondria, may require anywhere from 1-6 hours, with varying forms of protein and a varying level of varying glycemic foods supplying variable energy. Jeff notes that he and Cory (former Mrs. Everson and six time Ms. Olympia) used to eat for 2 hours and go straight to the gym and Jeff has been doing that since he was 15. The again, he is a cheese head.

At any rate, most bodybuilders train on an empty gut for one to two hours. Assuming they start to eat their biggest protein meal after showering and getting home, about 30 minutes to an hour after they train, a bodybuilder may have gone 4-5 total hours on an empty gut.

In such a case the oft-recommended high whey anabolic protein after training may not be optimal, as the aminos might be diverted for liver oxidation instead of for muscle substrate restoration and myofiber structural demands. This is especially true for someone on a reduced carb diet. The same can be said for an all-whey at breakfast after 6-9 hours of sleep!

Whey protein ingested as a first meal or at 30 minutes to an hour after training, if on an empty gut, should definitely be combined with other foods to actually slow its absorption. One should time meals and nutrients to take advantage of the enormous anabolic potential of whey, especially in the form of isolates and hyrolysates.

Terry Giles, the lead formulator of the original Cybergenics, who now works for Numico/Rexall-Sundown’s Met-Rx says, “Metabolically, amino acids from whey can be digested and absorbed almost too quickly, there isn’t much time for the nitrogen to be used for muscle-building. Instead the liver uses this extra shower of amino acids for energy, especially if one is ingesting fewer fats and carbohydrates like bodybuilders do.

Phil Connolly, who creates the 3 top-end proteins in the Dorian Yates Approved ProPeptide Line, adds, “Some forms of whey, notably higher lactose concentrates, prove problematic to the intestine. If they are more denatured, they have been changed from their native structure because of processing (being denatured). This is one of the reasons. The DY-Approved Co. took a more expensive lead and better suited to bodybuilders, to use low temperature native micellar casein. Native casein has a slower, steadier absorption and this is seriously critical to adults, especially 35 and older.”

Mr. Connelly continues, “The denaturation of dairy proteins causes poor digestion leading to cramping, bloat and water retention. While undenatured protein sits in the intestines, it can ferment. It can’t be hydrolyzed and more and more water floods in to deal with this, so you get bloat. Now, this is even more of a concern if anaerobic organism levels (such as yeast and mold) are higher. Most steroid users, or people using antibiotics, have killed a lot of their favorable digestion organisms. This is why both Dorian Yates Approved ProPeptide and VPX add valuable probiotics to their protein base. As a concluding statement on this issue, the greater the lactose intolerance (or any intolerance), the greater the potential for nausea, gas and bloat. Relative to whey, it is not the fast absorption, it is instead, the poor digestion at level of the small intestine.”

WHEY PEPTIDES CASEIN PEPTIDES

None of the above negates the value of worthiness of quality whey. On the contrary, good whey is more anabolic than anything, so you should use the highly anabolic biological characteristics of whey, correctly (see chart at very end).

B: Our top 7 in the mixed caseinate/ whey category, based on amino acid profile, species purity and lab tests:

• Beverly Ultra Size

• CA Labs Pure Gro

• Priced Right Proteus 8

• Optimum Pro Complex

• MET-Rx

• Labrada Lean Body

• Prolab Matrix

C: Our top two in the mixed micellar casein/whey category:

• Dorian Yates Approved ProPeptide or Pro-MR (both low temperature processed).

• VPX Micellean Bioactive Food

The Commercial Proteins Group is the only place in the world with pure micellar casein and supplies it to Dorian Yates Approved and VPX Micellean Bioactive Food. They also provide high-grade whey to several top companies like Beverly and Optimum. They have also reached the level of GMP and they only use the finest quality ingredients and flavorings (for instance sucralose costing $217/pound and some vanilla flavorings costing $60/pound). They consistently produce high quality proteins. The Dorian Yates Approved ProPeptide also contains 4-grams of glutamine per serving and is 98% lactose free. While Micellar casein is a more expensive than calcium, sodium or potassium caseinate, all casein/caseinates digest at a slower rate, taking longer to be absorbed and utilized. Casein/caseinate takes more time to be digested in the gut, releasing amino acids at a much slower pace into the bloodstream. Experts have described casein as “more of an anti-catabolic sprinkling of amino acids, not a whey anabolic down pour. And the drizzle is like a Feb. CA rain, it goes on and on and on for an extended period of time.”

Beverly’s Roger Riedinger says, “Ideally (and serious bodybuilders are both idealists and realists) should use a isolate and peptide whey like Muscle Provider when anabolic needs are high and a quality multiple mixed casein blend (Ultra Size) when catabolism is the enemy, such as bedtime and breakfast. We are the ONLY Company that offers every bodybuilder a special price on a combination just like this — the only one.”

Dr. Eric Serrano, obesity specialist, who supervises the nutrition of dozens of pro athletes and has zero financial interest in any protein, calls the Beverly stack the US/MP stack, the Ultimate anti-catabolic-anabolic protein stack.

Most companies indeed, do not produce the two kinds of base protein, going more whey or more casein-based. If you eat a protein source once or twice a day with meals spaced too far apart, definitely use a protein with whey isolates such as BioPlex or combo protein concentrates /isolates / peptides, milk protein isolates, casein/caseinates and egg albumen (egg white).

[Jeff Everson’s note: In general, compared to whey and casein as a sole protein source, soy is not as complete. Protein sources should be mixed. However, soy isolate is very high in BCAA, glutamine and arginine. If you are male and have been a user of steroids and/or have a family history of prostate cancer or you are female with a family history of either breast or ovary cancer, then look for a mixed blend protein that might also contain some minimal high grade soy isolate protein (CA Labs Pure Gro). Soy isolate has been well researched in these regards. Some soy flavones have been demonstrated to actually improve kidney function and to inhibit conversion of testosterone to DHT in the male. Research suggests that some soy flavones prohibitively mitigates prostate damage in the male and inhibits breast and ovary pre-cancerous cell proliferation in females. The commonly held nuance that somehow quality soy would ‘feminize’ adult bodybuilding males or lower testosterone, while anecdotal among bodybuilders, is over-stated. There have been no blind or double blind randomized adult bodybuilding studies that suggest soy isolate disinhibits myofibril hypertrophy, secondary to exercise. There is more suggestion that children and juveniles should not rely on soy as a sole protein source for optimum growth.]

Summary:

1: Use fast-acting quality whey protein fractions for instant availability when pure anabolism is desired, but never on an empty stomach! Examples: Optimum, Beverly Muscle Provider, Bioplex.

2: Use medium speed and high nitrogen content of caseinate, egg albumen/beef plasma for interim protein exposure Examples: Beverly Ultra Size, Beverly 100% Egg.

3: Use milk isolates/caseinate protein fractions for the “extended or prolonged” protein exposure, as well as whey components Examples: Priced Right, CA Labs Pure Gro, Labrada Lean Body, MET-Rx White Pak, MET-Rx APM 60, (both with metamyosyn), Prolab Lean Mass Matrix.

4: Use the above with micellar casein at super low temps, fractionated whey and probiotics. Ex: Dorian Yates Approved ProPetide, Pro-MR, Propetide MBF (mass).

Besides anabolic anti-catabolic content, proteins must be considered for important factors such as special absorption carriers like aminogen and glutamine peptides found in Optimum APS and gut health and protection agents, (and also for better absorption), like again glutamine peptides and unique probiotics, exclusively in Dorian Yates Approved ProPetide and VPX Micellan.

Also to be considered are cost, taste, availability, accessory nutrients, carbs, simple sugars and fats and the type and amount of oils, artificial agents, aspartame, sweeteners/maltodextrins used.